The GammaLib is a versatile toolbox for the high-level analysis of astronomical gamma-ray data. It is implemented as a C++ library that is fully scriptable in the Python scripting language. The library provides core functionalities such as data input and output, interfaces for parameter specifications, and a reporting and logging interface. It implements instruments specific functionalities such as instrument response functions and data formats. Instrument specific functionalities share a common interface to allow for extension of the GammaLib to include new gamma-ray instruments. The GammaLib provides an abstract data analysis framework that enables simultaneous multi-mission analysis.