MYRIAD is a C++ code for collisional N-body simulations of star clusters. The code uses the Hermite fourth-order scheme with block time steps, for advancing the particles in time, while the forces and neighboring particles are computed using the GRAPE-6 board. Special treatment is used for close encounters, binary and multiple sub-systems that either form dynamically or exist in the initial configuration. The structure of the code is modular and allows the appropriate treatment of more physical phenomena, such as stellar and binary evolution, stellar collisions and evolution of close black-hole binaries. Moreover, it can be easily modified so that the part of the code that uses GRAPE-6 could be replaced by another module that uses other accelerating-hardware like the Graphics Processing Units (GPUs). Appropriate choice of the free parameters give a good accuracy and speed for simulations of star clusters up to and beyond core collapse. The code accuracy becomes comparable and even better than the accuracy of existing codes when a number of close binary systems is dynamically created in a simulation; this is due to the high accuracy of the method that is used for close binary and multiple sub-systems. The code can be used for evolving star clusters containing equal-mass stars or star clusters with an initial mass function (IMF) containing an intermediate mass black hole (IMBH) at the center and/or a fraction of primordial binaries, which are systems of particular astrophysical interest.