Gen TSO estimates signal-to-noise ratios for transit/eclipse depths through an interactive graphical interface, similar to the JWST Exposure Time Calculator (ETC). This interface leverages the ETC by combining its noise simulator, Pandeia, with additional exoplanet resources from the NASA Exoplanet Archive, the Gaia DR3 catalog, and the TrExoLiSTS database of JWST programs. Gen TSO calculates S/Ns for all JWST instruments for the spectroscopic time-series modes available as of the Cycle 4 GO call. It also simulates target acquisition on the science targets or, when needed, on nearby stellar targets.