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T-PHOT extracts accurate photometry from low-resolution images of extragalactic fields, where the blending of sources can be a serious problem for accurate and unbiased measurement of fluxes and colors. It gathers data from a high-resolution image of a region of the sky and uses the source positions and morphologies to obtain priors for the photometric analysis of the lower resolution image of the same field. T-PHOT handles different types of datasets as input priors, including a list of objects that will be used to obtain cutouts from the real high-resolution image, a set of analytical models (as .fits stamps), and a list of unresolved, point-like sources, useful for example for far-infrared wavelength domains. T-PHOT yields accurate estimations of fluxes within the intrinsic uncertainties of the method when systematic errors are taken into account (which can be done using a flagging code given in the output), and handles multiwavelength optical to far-infrared image photometry. T-PHOT was developed as part of the ASTRODEEP project (www.astrodeep.eu).