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UVMULTIFIT, written in Python, is a versatile library for fitting models directly to visibility data. These models can depend on frequency and fitting parameters in an arbitrary algebraic way. The results from the fit to the visibilities of sources with sizes smaller than the diffraction limit of the interferometer are superior to the output obtained from a mere analysis of the deconvolved images. Though UVMULTIFIT is based on the CASA package, it can be easily adapted to other analysis packages that have a Python API.
The CASA (1107.013) task FAKEOBS generates model visibilities from already-existing measurement sets. This task can be used to substitute all the visibilities of the target with simulations computed from any model image. The measurement can either be with real or simulated data, the target can have been observed in mosaic mode, and there can be several sources (e.g., bandpass calibrator, flux/phase calibrator, and target).