CosmoHammer is a Python framework for the estimation of cosmological parameters. The software embeds the Python package emcee by Foreman-Mackey et al. (2012) and gives the user the possibility to plug in modules for the computation of any desired likelihood. The major goal of the software is to reduce the complexity when one wants to extend or replace the existing computation by modules which fit the user's needs as well as to provide the possibility to easily use large scale computing environments. CosmoHammer can efficiently distribute the MCMC sampling over thousands of cores on modern cloud computing infrastructure.