EXO-NAILER (EXOplanet traNsits and rAdIal veLocity fittER) efficiently fits exoplanet transit lightcurves, radial velocities (RVs) or both. The code handles data taken with different instruments. For RVs, a different center-of-mass velocity can be fitted for each instrument to account for offsets between them; if jitter is included, a different jitter term can also fitted for each instrument. For transits, a different photometric jitter can be fitted to each instrument as can different limb-darkening coefficients and different transit depths. In addition to general options that need to be set, EXO-NAILER also requires that photometry and radial velocity options be defined for each instrument.