SoFiA 2 is a fully automated spectral-line source finding pipeline originally intended for the detection of galaxies in large HI data cubes. It is a reimplementation of parts of the original SoFiA pipeline (ascl:1412.001) in the C programming language and uses OpenMP for multithreading, making it substantially faster and more memory-efficient than its predecessor. At its core, SoFiA 2 uses the Smooth + Clip algorithm for source finding which operates by spatially and spectrally smoothing the data on multiple scales and applying a user-defined flux threshold relative to the noise level in each iteration. A wide range of useful preconditioning and post-processing filters is available, including noise normalization, flagging of artifacts and reliability filtering. In addition to global data products and source catalogs in different formats, SoFiA 2 can also generate cutout images and spectra for each individual detection.