pybranch calculates experimental branching fractions and transition probabilities from measurements of atomic spectra. Though the program is usually used with spectral line lists from intensity-calibrated spectra from Fourier transform spectrometers, it can in principle be used with any calibrated spectra that meet the input requirements. pybranch takes a set of linelists, computes a weighted average branching fraction (Fki) for each line, combines these branching fractions with the level lifetime to obtain the transition probability, and then prints the calibrated intensities and S/N ratios for all the lines observed from a particular upper level in each spectrum. One line can be chosen to use as a reference to put all of the intensities on the same scale. pybranch can use calculated transition probabilities to calculate a residual from lines that have not been observed.