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The Exoplanet Detection Map Calculator (Exo-DMC) performs statistical analysis of exoplanet surveys results using Monte Carlo methods. Written in Python, it is the latest rendition of the MESS (Multi-purpose Exoplanet Simulation System, ascl:1111.009). Exo-DMC combines the information on the target stars with instrument detection limits to estimate the probability of detection of companions within a user defined range of masses and physical separations, ultimately generating detection probability maps. The software allows for a high level of flexibility in terms of possible assumptions on the synthetic planet population to be used for the determination of the detection probability.