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Fermipy facilitates analysis of data from the Large Area Telescope (LAT) with the Fermi Science Tools. It is built on the pyLikelihood interface of the Fermi Science Tools and provides a set of high-level tools for performing common analysis tasks, including data and model preparation with the gt-tools, extracting a spectral energy distribution (SED) of a source, and generating TS and residual maps for a region of interest. Fermipy also finds new source candidates and can localize a source or fit its spatial extension. The package uses a configuration-file driven workflow in which the analysis parameters (data selection, IRFs, and ROI model) are defined in a YAML configuration file. Analysis is executed through a python script that calls the methods of GTAnalysis to perform different analysis operations.