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PythonPhot is a simple Python translation of DAOPHOT-type (ascl:1104.011) photometry procedures from the IDL AstroLib (Landsman 1993), including aperture and PSF-fitting algorithms, with a few modest additions to increase functionality and ease of use. These codes allow fast, easy, and reliable photometric measurements and are currently used in the Pan-STARRS supernova pipeline and the HST CLASH/CANDELS supernova analysis.