Nii-C implements a framework of automatic parallel tempering Markov Chain Monte Carlo. Parameters ensure an efficient parallel tempering process that is set by a control system during the initial stages of a sampling process. The autotuned parameters consist of two parts: the temperature ladders of all parallel tempering Markov Chains, and the proposal distributions for all model parameters across all parallel tempering chains. Written in C, Nii-C supersedes the Python code Nii (ascl:2111.010). Nii-C is parallelized using the message-passing interface protocol to optimize the efficiency of parallel sampling, which facilitates rapid convergence in the sampling of high-dimensional and multimodal distributions, as well as the expeditious code execution time. The code can be used to trace complex distributions due to its high sampling efficiency and quick execution speed.