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Astropy provides a common framework, core package of code, and affiliated packages for astronomy in Python. Development is actively ongoing, with major packages such as PyFITS, PyWCS, vo, and asciitable already merged in. Astropy is intended to contain much of the core functionality and some common tools needed for performing astronomy and astrophysics with Python.
CosmoloPy is a suite of cosmology routines built on NumPy/SciPy. Its capabilities include various cosmological densities, distance measures, and galaxy luminosity functions (Schecter functions). It also offers pre-defined sets of cosmological parameters (e.g., from WMAP), conversion in and out of the AB magnitude system, and the reionization of the IGM. Functions take cosmological parameters (which can be numpy arrays) as keywords and ignore any extra keywords, making it possible to build a dictionary of cosmological parameters and pass it to any function.