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mhealpy extends the functionalities of the HEALPix (ascl:1107.018) wrapper healpy (ascl:2008.022) to handle single and multi-resolution maps (a.k.a. multi-order coverage maps or MOC maps). In addition to creating and analyzes MOC maps, it supports arithmetic operations, adaptive grids, resampling of existing multi-resolution maps, and plotting, among other functions, and reads and writes to FITS, which enables sharing spatial information for multiwavelength and multimessenger analyses.